FACULTY PROFILE
Dr. C. Madhava Reddy
Assistant Professor
+91 9703599690
cmreddy@yogivemanauniversity.ac.in
Qualification :
Ph.D in Animal Sciences, University of Hyderabad, Hyderabad.
Experience :
- Post doctoral fellow (2002-06) & Research Scientist (2006-09)U T MD Anderson Cancer Center, Texas, USA Burnham Research Institute, California, USA
Area/s of research interests :
Molecular mechanisms of DNA damage recognition and repair, Aging, Natural products as a therapeutic agents.
Achievements/Awards :
- Dr Reddy’s Research Foundation Fellowship
- AP-Netherlands Fellowship
Details of significant paper publications :
  1. Lange SS1, Reddy MC1 , Vasquez KM. Human HMGB1 directly facilitates interactions between nucleotide excision repair proteins on triplex-directed psoralen interstrand crosslinks. DNA repair 8: 865-872, 2009. 1 Authors contributed equally.
  2. Suraneni V.K. Mahipal, Jagu Subhashini, Reddy MC, Metukuri M. Reddy, Kotha Anilkumar, Karnati R. Roy, Gorla V. Reddy and Pallu Reddanna. Effect of 15-lipoxygenase metabolites, 15-(S)-HPETE and 15-(S)-HETE on chronic myelogenous leukemia cell line K-562: Reactive oxygen species (ROS) mediate caspase-dependent apoptosis. Biochem Pharmacol. 15: 202-214, 2007
  3. Reddy MM, Mahipal SV, Subhashini J, Reddy MC, Roy KR, Reddy GV, Reddy PR, Reddanna P. Bacterial lipopolysaccharide-induced oxidative stress in the impairment of steroidogenesis and spermatogenesis in rats. Reprod Toxicol. 22:493-500, 2006.
  4. Reddy MC, Vasquez KM. Repair of Genome Destabilizing Lesions. Rad. Research. 164: 345-356, 2005. (invited article) Thoma BS, Wakasugi M, Christensen J, Reddy MC, Vasquez KM. Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks. Nucleic Acids Res. 33:2993-3001, 2005.
  5. Reddy MC, Christensen J, Vasquez KM. Interplay between human high mobility group protein 1 and replication protein A on psoralen-cross-linked DNA. Biochemistry. 44:4188-4195, 2005.
  6. Subhashini J, Mahipal SV, Reddy MC, Mallikarjuna Reddy M, Rachamallu A, Reddanna P. Molecular mechanisms in C-Phycocyanin induced apoptosis in human chronic myeloid leukemia cell line-K562. Biochem Pharmacol. 68:453-462, 2004.
  7. Reddy MC, Subhashini J, Mahipal SV, Bhat VB, Srinivas Reddy P, Kiranmai G, Madyastha KM, Reddanna P. C-Phycocyanin, a selective cyclooxygenase-2 inhibitor, induces apoptosis in lipopolysaccharide-stimulated RAW 264.7 macrophages. Biochem Biophys Res Commun. 304:385-392, 2003.
  8. Reddy CM, Bhat VB, Kiranmai G, Reddy MN, Reddanna P, Madyastha KM. Selective inhibition of cyclooxygenase-2 by C-phycocyanin, a biliprotein from Spirulina platensis. Biochem Biophys Res Commun. 277:599-603, 2000.